[01] Parviz Deihimy, Torabinejad Dental Research Center, Department of Oral and Maxillofacial Pathology, Scholar Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran. [02] Neda Karghahi, Dental Implants Research Center, Department of Oral and Maxillofacial Pathology, Scholar Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran. [03] Saeedeh Khalesi, Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Sadoughi University of Medical sciences, Yazd, Iran.

Introduction: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant lesion arising within the jawbones, without initial connection with the oral mucosa. This malignant lesion develops from odontogenic epithelium or odontogenic cysts or tumors. Case Report: In this case report, an intraosseous squamous cell carcinoma arising from an odontogenic cyst in a 60-year-old male patient is presented. Conclusion: This case report demonstrates the importance of clinician’s knowledge of malignant potential of odontogenic cyst and the accurate and timely management and treatment of these lesions.

Squamous Cell Carcinoma, Radicular Cyst

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